Paul Saladino· MD
the Obesity Paradox strikes again is you know apparently for some people it's better to have the extra weight because you know you know enough fasting and you're eating well to support the immune system then too fast
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
the Obesity Paradox strikes again is you know apparently for some people it's better to have the extra weight because you know you know enough fasting and you're eating well to support the immune system then too fast
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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is you know apparently for some people it's better to have the extra weight because you know you know you're not fasting and you're eating well to support the immune system than to fast because if you if your cortisol to DHA ratio is high enough and you raise it even further um I don't think anything good will come out of that.
Time-restricted eating produces fat loss independent of total calories.
A 72-hour fast measurably improves autophagy markers in healthy adults.
One-meal-a-day (OMAD) eating patterns increase all-cause mortality in long-running cohort data.
Eating the largest meal before 3pm improves 24-hour glucose vs. an evening-heavy schedule, calorie-matched.