there are folks like Brian Johnson who spend a lot of time in this category specifically you know taking very high doses of polyphenols limiting their caloric intake to just early part of the day I think he eats dinner at 11:00 a.m. I don't know if it's still qualifies as dinner at 11:00 a.m. but his final bite of calories is I believe at 11:00 a.m. doing everything from red light to PRP platelet platelet rich plasma excuse me um and essentially the kitchen sink approach to longevity and aging