A 382-day fast in a patient with high uric acid and weight loss did not impair metabolic health or insulin sensitivity, suggesting context mitigates uric acid harm.

“his labs look normal so is there something else going on here with metabolic health that is mitigating this level of uric acid is there a milieu here is there a context that we need to think about look at this his blood glucose just went down and down and down he got more uh healthy he got more insulin sensitive as his uric acid is massively high so where is in this case the uric acid causing major issues for this human as his um as his overall physiology just improves with weight loss”