Paul Saladino· MD
humans need to have some period without food and if you can't do that then your body is not metadata metabolically flexible and that's a problem
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
humans need to have some period without food and if you can't do that then your body is not metadata metabolically flexible and that's a problem
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i do think that most people most of us grow up like i did not not ever fasting not ever having any period that forces your body to become fat adapted and i think that that's important for all of us to achieve
humans need to have some period without food and if you can't do that then your body is not metabolically flexible and that's a problem
Time-restricted eating produces fat loss independent of total calories.
A 72-hour fast measurably improves autophagy markers in healthy adults.
One-meal-a-day (OMAD) eating patterns increase all-cause mortality in long-running cohort data.
Eating the largest meal before 3pm improves 24-hour glucose vs. an evening-heavy schedule, calorie-matched.