Exercise combined with caloric restriction or fasting can enhance autophagy.

“It is something that is activated. It's first of all, we have basil amount of autophagy going on at any point, right? Like that's happening like >> you don't have to fast. You don't have to fast >> or be in a caloric deficit which will also exacerbate it, >> right? You do have fasted activated autophagy and certain tissues are more sensitive like the liver and the brain actually and so you know we don't have a lot of human data on that in terms of like fasting. Exercise also activates it.”