Fasting for 2-3 days a week may not be sufficient for major health benefits; a protocol of eating one main meal within a 4-hour window daily is suggested.

Time-restricted eating produces fat loss independent of total calories.

A 72-hour fast measurably improves autophagy markers in healthy adults.

One-meal-a-day (OMAD) eating patterns increase all-cause mortality in long-running cohort data.

Eating the largest meal before 3pm improves 24-hour glucose vs. an evening-heavy schedule, calorie-matched.