A nutritional intervention of increased fruit and vegetable intake lowered circulating ceramides, including C24 ceramide, which is a known inhibitor of insulin signaling.

“we cannot you cannot ignore these people got metabolically healthier oh i agree their overall ceramides decreased where is the insulin resistance in these people stephen wait a minute paul it doesn't show here we shoved vegetables down their mouths and they got better in addition to two cups of fruit per day we'll have to do a separate podcast about the fallacy of polyphenols i knew you were going to say that with the vegetables but these people ate two cups of fruit this is a human study showing that ceramides went down”