The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
The push back on GLP1 says there are variety of reasons um probably a discussion for another time but they've clearly helped many many people uh as long as people still engage in the right behaviors muscle resistance training and people still need to take great care of themselves eat properly exercise sleep etc.
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
But what it does, it actually regulates that insulin. So when you eat, it spikes your insulin up and clears that sugar out of your blood, right? ... And it also makes you insulin sensitive. So again, clearing it, which is oxygen really for these PCOS patients.
As a field, we quickly accepted that they are hugely powerful for PCOS and states of obvious insulin resistance for reasons that make sense to everybody.
glp-1 receptor agonists may be promising to help with the weight management and the insulin resistance
And they're very successful as you know for weight loss and there have been some studies on PCOS patients specifically. Very effective.
Yeah. Yeah, they work really well just like they work in people with diabetes or people who with obesity without diabetes.
Yeah, increasingly and and they're very successful as you know for weight loss and there have been some studies on PCOS patients specifically very effective.