Bryan Johnson· Author
GLP-1’s raise your resting rate which can degrade sleep quality and lower HRV.
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
GLP-1’s raise your resting rate which can degrade sleep quality and lower HRV.
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Higher doses and prolonged exposure generally lead to more significant increases.
A meta-analysis of over 60 randomized clinical trials found the mean RHR increase with GLP-1RAs to be 2.11 bpm (95% CI: 1.68–2.54).
when they come off the drug usually within a month it goes back to normal
we're also seeing a compression of heart rate variability so we see heart rate variability come down
the unambiguous sign that we see is that resting heart rate is going up um and it's going up an average of 10 beats per minute with a range of about 8 to 12
and when they come off the drug usually within a month it goes back to normal
the unambiguous sign that we see is that resting heart rate is going up um and it's going up an average of 10 beats per minute with arrange about 8 to 12
we're also seeing a compression of heart rate variability so we see heart rate variability come down although that's less predictive