David Sinclair· PhD
Intriguing paper out Mon @AgingCell by Greg Fahy & Steve Horvath @UCLA - evidence human age can be reversed 2.5 years by combo of growth hormone + metformin & DHEA to prevent glucose spike.
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
Intriguing paper out Mon @AgingCell by Greg Fahy & Steve Horvath @UCLA - evidence human age can be reversed 2.5 years by combo of growth hormone + metformin & DHEA to prevent glucose spike.
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well there is an aging cell paper where somebody tried to rejuvenate the thymus and they took patients and gave them a growth hormone right growth hormone metformin and dhea yeah i was hiding that i think it's a metformin effect but they showed methylation reversal
A very small and preliminary trial found that treatment with growth hormone and two diabetes drugs (metformin and DHEA) was able to boost immune cell count, regenerate some of the aging thymus gland, and reverse epigenetic aging by 2.5 years in older men.