Paul Saladino· MD
with lectins specifically pha so phytohemaglutinin from red kidney beans and at least in mouse models you know admittedly animal models they showed that when they introduced phytohaemoglutinin the diversity of the gut went down right because e coli expanded one of these proteobacter expanded i thought wow that's kind of almost like a model sibo system by introducing a gut lectin and i they seem to think that the mechanism had to do with the lectins negatively affecting the the cells that produce mucus the goblet cells the lectins weren't necessarily associating with e coli they were associated with our gut and changing the way that it was producing mucus and creating holes in the mucous layer of the gut and then e coli was somehow able to contact the gut inflammation and overgrowth