A breathing technique involving three consecutive inhales through the nose, a 15-20 second breath hold, and a slow exhale can eliminate hiccups by hyperexciting and hyperpolarizing the phrenic nerve.

“This method of three inhales through the nose followed by a long exhale through the nose or mouth will eliminate hiccups right away because what it does is it hyperexcites the phrenic nerve three times in a row, a very unnatural pattern for the phrenic nerve to fire.”