Rhonda Patrick· PhD
The 4x4 interval workouts and the one-minute on, one-minute off protocols can typically be done twice a week.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
The 4x4 interval workouts and the one-minute on, one-minute off protocols can typically be done twice a week.
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