Andrew Huberman· PhD
And if estradiol gets too high, we think if it gets over about 55, 60, we will give micro doses of anastrozole. But it has to be real micro doses. I mean, you cannot pound people with anastrozole.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
And if estradiol gets too high, we think if it gets over about 55, 60, we will give micro doses of anastrozole. But it has to be real micro doses. I mean, you cannot pound people with anastrozole.
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We have to have it compounded at 0.1 milligrams, and we might give a patient 0.1, two to three times a week. That would be a big dose of anastrozole.
I'd say probably 20% of men require a micro dose of anastrozole to get into that range.