The preferred method of estradiol administration is via a branded FDA-approved patch, such as Vel dot, which can be trimmed and changed every 3-4 days.

“Our Preferred Product is an estradiol patch uh we use a branded version I actually when it comes to hormones I really prefer using branded versions of an FDA approved compound we prefer to use something called the Vel dot so it's an FDA approved estradiol patch a woman applies the patch you apply that you know the patch comes in different Doses and you can trim it if you want more or less estrogen and she changes it like every three or 4 days”