Steroids are lipids that absorb well, but their release into the bloodstream depends on liver processing or lymphatic transport.

“if you want most of it most of it obviously to be released in the bloodstream you have to bypass the leverage mentioned and there's this lymphatic transport which basically dumps them through the thoracic duct I think it's called so when you absorb from the intestine through the lymphatic system they this whatever is absorbed on the fire system does not go into the portal weight which in the port of the drains into the liver so it means your bypassing the liver and then whatever gets absorbed and the fact system most of it goes into the systemic circulation”

“if you mix the steroids um with these longer chain fatty acids most of those most of that steroid will actually go into your bloodstream”

“if you look in the literature you'll see that that it's been long known that steroids are bioavailable they're lipids uh the only question is when you absorb them and they do absorb very well how much of that gets sent to the liver which of course will process a lot of them and actually accumulate not necessarily excrete it will accumulate so that's why liver is a good source of steroids and then how much will it release in the bloodstream”