Excess estrogen and thymus function

PS

Paul Saladino13m · 2023-02-05

Claims Made

38

Claims Supported

33

Support Rate

87%

Support rate

33 of 38 claims supported

33 supported5 partial / not

Claims from this content

34

Well SupportedDesiccated cow brain appears beneficial for cognitive decline in controlled studies, a result not replicated by plant-based phosphatidylserine.Partially SupportedEating organ meats may provide signaling molecules like peptides that survive digestion and offer benefits beyond basic micronutrients.Well SupportedSteroids are lipids that absorb well, but their release into the bloodstream depends on liver processing or lymphatic transport.Well SupportedHigh estrogen levels are associated with higher than normal baseline cortisol levels, which can lead to thymic involution.Well Supported

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A. Volkovreader

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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

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Would love a "what would change this verdict" RSS feed. Sign me up if it exists.

Histamine immune support, potentially through desiccated thymus, is a recommended starting point for most autoimmune conditions.

Well SupportedCortisol is the primary driver of thymic atrophy, and anti-cortisol agents can halt this atrophy.

Partially SupportedLiver, fresh or desiccated, is a good source of copper and can help address potential copper deficiency.

Partially SupportedConsuming oral steroids with long-chain or medium-chain saturated fats may help bypass liver metabolism and increase bioavailability.

Partially SupportedConsuming desiccated or fresh thymus can improve the health and size of the thymic gland in animal models, enhancing immunologic function.

Partially SupportedProgesterone may be protective against COVID-19 severity in women, while estrogen may worsen the condition.

Partially SupportedAdministering progesterone can reverse thymic atrophy in rodents.

Partially SupportedThe heart may contain factors, such as testosterone, that protect it from chronic stress and high cortisol levels.

Partially SupportedThe brain is a significant steroidogenic organ, producing and accumulating large amounts of steroids.

Partially SupportedHistorically, desiccated glandular extracts from various glands were used to address issues like fertility (testicles), liver problems (desiccated liver), and thyroid function.

Partially SupportedEstrogen initiates tissue production and wound healing but must be turned off to prevent undifferentiated growth and potential cancer.

Partially SupportedBiomarkers of bone resorption can indicate elevated cortisol and thymic atrophy.

Partially SupportedEstrogen stimulates ACTH release and breaks HPA axis negative feedback, potentially leading to chronically higher cortisol.

Partially SupportedAdministration of ru-486 (mifepristone) led to better immune function and reduced susceptibility to viral diseases.

Partially SupportedExcess estrogen, potentially driven by TLR4 activation, can lead to thymic atrophy.

Partially SupportedConsuming desiccated testicle with butter or fat can serve as a form of testosterone replacement therapy.

Partially SupportedPregnenolone has a neurogenic effect and is being investigated in clinical trials for Alzheimer's.

Partially SupportedFats with chain lengths of 12 carbons or less go to the portal vein, while fats with chain lengths higher than 12 are absorbed via the lymphatic system.

Partially SupportedRU-486 has shown rapid and complete remission of aggressive leukemias and lymphomas in case studies.

Partially SupportedTamoxifen is being investigated in a clinical trial for treating leukemias and lymphomas.

Partially SupportedAdministering aromatase inhibitors can reverse age-related thymic atrophy.

Partially SupportedDesiccated thymus supplement may help replenish the thymus gland and improve immune system function.

Partially SupportedIndigenous cultures traditionally consumed the entire animal, including organs like the brain, tongue, and glands.

Partially SupportedDesiccated testicle from Heart & Soil contains bioavailable androgens.

Partially SupportedUncontrolled estrogen-driven mechanisms can lead to hematological cancers like leukemias and lymphomas.

Partially SupportedThe thymus gland shrinks with age, which may be a pathological process that can be reversed.

Partially SupportedOral testosterone undecanoate formulations were developed to improve absorption, with early versions resembling peanut butter.

Partially SupportedDesiccated liver extract could be a potential treatment for alcohol-related liver disease.

Partially SupportedPregnenolone accumulates in the brain at concentrations several hundred times higher than in the blood and has a pro-cognitive effect.

Partially SupportedConsuming oral steroids with long-chain or medium-chain saturated fats may improve bioavailability.