Andrew Huberman· PhD
There's a particular area of the hypothalamus called the ventromedial hypothalamus. And it's one that researchers have been interested for a long time now, in terms of its relationship to hunger and feeding. And the reason is, it creates these paradoxical effects. What do I mean by that? What they found was that sometimes lesioning, or disrupting the neurons in the ventromedial hypothalamus would make animals or people hyperphasia, they would want to eat crazy. And other lesions in other individuals or animals would make them anorexic, it would make them not want to eat at all. It would make food aversive.