The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
So there's basically three hormones, so genetics plays a huge role in this. There's no question that just out of the box, people have a different like set point for SHBG. Mine is incredibly low. My SHBG is like kind of in the 30s, 20s to 30s. But from a hormone perspective, there's basically three hormones that run it. So estradiol being probably the most important, insulin and thyroxine.
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
So if you have a person whose thyroid is out of whack, you have to fix that before you, if their T4 is out of whack, you're going to interfere with SHBG.