During puberty, kisspeptin stimulates GnRH and LH release, leading to testosterone production and secondary sexual characteristics.

“now that raises the question what turns on GnRH and the signal that turns on G&R is kisspeptin kisspeptin in other words is further Upstream from G&R and lsh and FSH it's a Cascade it goes kisspeptin GnRH LH FSH testosterone estrogen okay that's the pathway”

“it's very clear that kisspeptin is involved in the activation of puberty the transition from prepubertal to postpubertal stages of life it's also involved in any of the sort of Downstream effects of having elevated LH and FSH including elevated Vitality which includes both energy and in some cases libido”

“the brain turns on the hormone systems that allow puberty to occur one of the more interesting molecules that triggers puberty in all individuals is something called kisspeptin k i SS p p e t i n kisspeptin kisspeptin is made by the brain and it stimulates large amounts of a different hormone called GnRH gonadotropin releasing hormone to be released gonadotropin releasing hormone then causes the release of another hormone something like called luteinizing hormone or LH which travels in the bloodstream and stimulates the ovaries of females to produce estrogen and the testes of males to produce testosterone”

“so in puberty testosterone leads to further growth and development of the penis as well as the accumulation of or growth of pubic hair uh deepening of the voice all the secondary sexual characteristics”