High testosterone or estrogen levels can negatively feedback and shut down luteinizing hormone (LH) production.

“remember that the testicles making uh making testosterone but there's a negative feedback that negative feedback testosterone goes back and feeds back negatively on the pituitary and also on the hypothalamus but also estrogen goes back and feeds back negatively”

“Um, and then there's also like some stimulation of progesterone receptors that causes negative feedback as well. um among other things too. But the primary that are to be noted probably for this discussion, androgen receptors, estrogen receptors, when those are satisfactory or in a adequate amount um stimulated, it will tell your brain, okay, we have enough testosterone as well as DHT and estrogen that we don't need to make more essentially because we have, you know, a satisfied amount of estrogen receptor activation in the body. So we need to like clamp down and not make as much hormones because we don't want to have too much. So that will give negative feedback to the hypothalamus, pituitary, testicular axis to not produce as much G&RH and LH and FSH until those levels fall to where there's a need to make more hormones.”