Androgens like testosterone can increase sebum production and cause hair follicle hypertrophy, contributing to acne.

“the accumulation of that sebum in the follicle can be due to a number of different things some of it can be related to androgens things like testosterone increasing the amount of sebum that's produced okay this is why you often see acne during puberty in addition the anabolic the progrowth effects of androgens such as testosterone and by the way these occur in both males and females because both males and females have testosterone and estrogen the androgenic effects of testosterone can also cause hypertrophy growth of the hair follicle”