Andrew Huberman· PhD
You can lower estradiol a bit with an aromatase inhibitor, and that can bring down SHBG.
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You can lower estradiol a bit with an aromatase inhibitor, and that can bring down SHBG.
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so corre isn't it about 85% of the Androgen binding is coming through shbg yeah so well it it depends a little on how how much you have but that's roughly the idea right so it it if that is to answer your question depends a little bit on how much shbg you have but most of the binding is through shbg and a small small percentage is for through Alum and um
SHBG and your binding proteins like what's your baseline relative to after? Because if you are injecting infrequently or a dose that is significantly suppressive like it might otherwise be a proxy for like using more than you might need. Not necessarily the case always, but SHBG will get suppressed dramatically by exogenous androgens in a dose dependent manner.