Individuals with a deficiency in 5-alpha reductase can appear feminized early in life and then masculinize at puberty, developing a penis.

“There's actually a name for this it's called hosis which the translation is more or less penis at 12 and as strange as this might sound it makes sense if you understand the underlying mutation what happens in these children these whid dois is that the child is born it as testes which are not descended so up in the body they weren't able to convert testosterone to dihydro testosterone because they lack”

“people you know would have kids where they would look feminized early on because they have a deficiency in five alpha reductase no DHT production and then at 12 they would become you know mascized they' sprout a penis”

“So we can go back to the condition we talked about earlier, you know, where the at puberty you sprout penis because you had a deficiency in alpha reductase. So you're not picking DHT, right? So these kids were raised as girls because there's no the extrogenitalia look like they're feminized. But as soon as you know they hit puberty and they start getting realized, they get this part of penis as you put it. Um many of them switch over to being boys and becoming men happily I guess.”

“So they're born appearing female. They have SRY, the gene, this deterministic gene. They make testosterone. It doesn't convert to dihydrotestosterone. Then puberty rolls around and they go from having what the parents and they thought was a vagina and a clitoris and they sprout a penis.”

“And then my understanding is there's also a mutation where um people lack the enzyme that converts testosterone to dihydrotestosterone. So they're born appearing female. They have SRY, the gene, this deterministic gene. They make testosterone. It doesn't convert to dihydrotestosterone. Then puberty rolls around and they go from having what the parents and they thought was a vagina and a clitoris and they sprout a penis.”