The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
How does GLP-1 reduce appetite? It does that, in part, by changing the activity of neurons in the hypothalamus, this cluster of neurons just above the roof of our mouth, that themselves make GLP-1 and that cause the activation of motor circuits for reaching, chewing, all the things that we associate with feeding behavior.
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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GLP-1 tends to inhibit feeding and tends to reduce appetite.
It does that by activating certain neurons in your hypothalamus. So that's a brain region that controls hunger and satiety. It makes us feel full at the level of the brain, so it makes us feel sated, that is. And it actually makes us feel full.
is that glp1 acts more or less as an appetite suppressant so