Estradiol levels fluctuate significantly during the normal reproductive cycle, ranging from approximately 50 pg/mL to over 3000 pg/mL during pregnancy.

“So so probably let's say 50 is your low. Then you go to ovulate and that's in your midcycle and usually it's about 150 let's sayish maybe it's 200 300 whatever it is pregnancy your level is 3,000 or higher right is very high and so if you're in your normal reproductive cycle you go from 50 to 150 so let's use the gas tank analogy you're at a quarter tank at 50 and you go to 3/4 tank at 150 then down to a quarter tank you can drive wherever you want to go you know during that time”