Andrew Huberman· PhD
we can define stress very specifically as times when adrenaline also called epinephrine and or norepinephrine also called noradrenaline, are elevated in your body.
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we can define stress very specifically as times when adrenaline also called epinephrine and or norepinephrine also called noradrenaline, are elevated in your body.
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So you release norepinephrine from a site in the brain very quickly as well in parallel with that release of adrenaline.
That very rapid response occurs also because of the HPA axis, but because of the release of adrenaline, epinephrine and norepinephrine from your adrenals and also from areas in your brain.
your brain note something stressful is happening within two seconds your hypothalamus is secreting that CRH which within about 10 seconds is getting your pituitary to release a hormone called ACTH which within about 30 seconds has gotten to your adrenals and you are slowly starting the glucocorticoid component of your stress response