Andrew Huberman· PhD
I would say there's another factor which is being female is a health hazard so we've twice the rate of depression insomnia we've got 3 to 4X increased risk of multiple sclerosis we've got 5 to8 times the risk of thyroid dysfunction so if you just look at that and you look at subtle preclinical thyroid dysfunction a huge number of the women that I take care of well let me back off a large number of the women that I take care of have thyroid dysfunction that's contributing to constipation and if we go back to that control system the hypothalamic pituitary adrenal thyroid gatal gut AIS and they have a lot of perceived stress together with this borderline thyroid function that no mainstream medicine doctor has told her is a problem and then she's got a problem with the Tango between estrogen and progesterone she's going to tend toward constipation women have a lot more constipation than men the gut is about 10t longer in women compared to men we should talk about some sex and gender differences and Define those sure and they are much more likely to have a torturous colon and the way you know that is you get a colonoscopy and they tell you yeah it's really hard to like get in there do what we need to do