We can't find evidence that holds up here. Proponents are reasoning from mechanism or analogy rather than direct human data, and the most credible skeptics raise objections we can't dismiss.
So the relative risk increase of breast cancer in the estrogen plus MPA group versus the placebo was 25, 27%. And that became the only headline. HRT increases risk of breast cancer by 27%. Now, I don't think that's true at all today, but let's even look at the data. What was the ARR? What was the absolute risk increase? It was a difference between five cases per thousand and four cases per thousand. So the ARR was 0.1%, one case in a thousand.
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
For symptomatic perimenopausal women under 60, hormone replacement therapy reduces all-cause mortality.
The breast-cancer risk attributed to HRT in the original WHI trial was overstated and the timing window matters most.