The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
I think it's very well understood that two of the biggest risk factors for cardiovascular disease are smoking and hypertension I don't think there is any ambiguity that cigarette smoking and high blood pressure increase the risk of cardiovascular disease and they both appear to do so through a mechanism that weakens the endothelium or creates an injury to the endothelium
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
it's very well understood that two of the biggest risk factors for cardiovascular disease are smoking and hypertension I don't think there is any ambiguity that cigarette smoking and high blood pressure increase the risk of cardiovascular disease and they both appear to do so through a mechanism that weakens the endothelium or creates an injury to the endothelium
so some combination of elevated glucose elevated insulin and other metabolic byproducts such as homocystine uric acid all of these things serve to weaken the endothelium along with elevated blood pressure and smoking and that creates a greater susceptibility again it's not surprising that all of those things pose about an equal risk to cardiovascular disease as does the presence of elevated apob