Paul Saladino· MD
If you give someone pioglitazone, it also improves their blood pressure. Reversing insulin resistance, even with a medication, improves blood pressure. Check out this paper. The effects of pioglitazone on metabolic control and blood pressure, a randomized study in patients with type 2 diabetes mellitus. Conclusions, the study demonstrates the efficacy of pioglitazone 30 mg a day and 45 mg a day in the treatment of type 2 diabetes with an improved lipid profile, because we know that improving insulin resistance improves the lipid profile, LDL goes down, HDL goes up, triglycerides go down, and decreased blood pressure in addition to improved glycemic control.