Chronic elevation of norepinephrine and epinephrine, especially late in the day, can reduce the number and efficiency of immune cells. — Whalespan
Chronic elevation of norepinephrine and epinephrine, especially late in the day, can reduce the number and efficiency of immune cells.
⚠ High risk
We can't find evidence that holds up here. Proponents are reasoning from mechanism or analogy rather than direct human data, and the most credible skeptics raise objections we can't dismiss.
✕NOTSUPPORTED
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High-risk intervention — consult a physician before acting.Drug-drug interactions, dose-dependence, and screening contraindications apply.
“However, if norepinephrine and epinephrine are elevated chronically, and especially if they are elevated late in the day repeatedly over many, many days, that can cause reductions in the number and efficiency of immune cells in combating infections.”