Epigenetic aging clocks accelerated by five years immediately after radiation and chemotherapy for head and neck cancer, remaining elevated a year later for those with persistent high inflammatory cytokines.

“there was a study that was uh done by dr levine and colleagues where people who had head and neck cancer that were undergoing radiation and chemotherapy treatment combined their epigen they had this treatment done and immediately after their treatment their epigenetic clocks accelerated by five years so it's like they had aged five years six months to a year later um they're at most people's epigenetic aging clocks were turned back to baseline returned back to normal except for people who still had elevated inflammatory cytokines those individuals with an elevated inflammatory cytokines at the six-month mark or one year mark after their treatment still had massively aged epigenetic aging clocks”