Peter Attia· MD
So as I kept seeing more and more data on this over the last 15 years or so, I became convinced that the act of being insulin resistant or the state of being insulin resistant in humans sets them up to accelerate tumor growth.
The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
So as I kept seeing more and more data on this over the last 15 years or so, I became convinced that the act of being insulin resistant or the state of being insulin resistant in humans sets them up to accelerate tumor growth.
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
And cancer cells tend to have more insulin receptor than the tissue from which they emerged. So in the process of tumors growing out, evolving, they turn up the expression of the insulin receptor, and that allows them to respond to insulin better.
And so we've known for a long time that if you have high levels of insulin, you can make almost any cancer cell grow better than just pure fetal calcium, which already has some insulin, and it's variable from batch to batch.