Paul Saladino· MD
The key enzyme in the salvage pathway for NAD+ is NAMPT, and this is negatively impacted massively by pathological insulin resistance…
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The key enzyme in the salvage pathway for NAD+ is NAMPT, and this is negatively impacted massively by pathological insulin resistance…
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to regenerate an nad you need an enzyme called nam pt well guess what when you are insulin resistant when you are metabolically broken man pt doesn't work as well
with nad i think the most interesting thing is that enzyme nam pt and that when people are insulin resistant and ampt doesn't work as well because nam pt is the main way that humans regenerate nad in the human body and so i've done a couple of podcasts about this on my podcast which is called fundamental health i think again we're back to metabolic health and insulin resistance as the primary the primary good things or the reverse of those being the primary drivers of chronic illness even nad depletion as we age because that enzyme mpt won't regenerate the nad
to regenerate n NAD you need an enzyme called NM PT well guess guess what when you are insulin resistant when you are metabolically broken n PT doesn't work as well