Paul Saladino· MD
the higher the ratio between fadh2 and nadh2 at the level of the mitochondria the more insulin resistance that is created
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
the higher the ratio between fadh2 and nadh2 at the level of the mitochondria the more insulin resistance that is created
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Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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a lowering f to n ratio means that your cells remain pathologically insulin sensitive when they're really supposed to be insulin resistant or at least have the signal that they're full