Paul Saladino· MD
when you eat palmitate in your diet it doesn't raise your serum palmitate so this is where i think plant-based advocates go a little awry they go a little astray they think oh it's the same but this isn't true
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
when you eat palmitate in your diet it doesn't raise your serum palmitate so this is where i think plant-based advocates go a little awry they go a little astray they think oh it's the same but this isn't true
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My entire post-doal fellowship was looking at I shouldn't say entire my biggest paper ever published was looking at the degree to which different fatty acids are capable of causing insulin resistance through the conversion into ceramides. And I'm going to upset some people, but in cell cultures and if you treat cells with saturated fat, pulmitate, which is the main saturated fat in the body, you get insulin resistance very quickly. Now, if you block ceramides, you resolve that insulin resistance. If you treat those cells with monounsaturated fatty acid, no insulin resistance. If you treat those cells with polyunsaturated fatty acid, no insulin resistance.