Insulin resistance can be caused by inflammation, infection, pathogens, gut dysbiosis, and overfeeding of mixed macronutrients.

“insulin resistance to me caused by multiple things it could be caused by inflammation we know that we can get insulin resistant when we get an infection if we're really sick for some reason like if we get the flu we'll get insulin resistant it can be caused by inflammation from a pathogen it can be caused the inflammation from disordered things in the gut I think which is part of what I'm so interested in with plant toxins and potentially disrupting gut barriers it can also be caused by overfeeding mixed macronutrients”