Eating saturated fats like stearic and palmitic acid leads to insulin resistance in fat cells.

“the way you get fat cells that are insulin resistant is by eating saturated fat and this has been shown time and time again that if you increase the amount of palmitic acid and stearic acid in the diet your fat cells become insulin resistant”

“the theory is this when you eat saturated fat when you eat stearic acid or palmitic acid because of the way that is beta oxidized in the mitochondria the fadh2 to nadh2 ratio makes the cells of your adipocytes makes your adipocytes insulin resistant meaning they don't get bigger meaning that the signal from your diet both for satiety at the level of the hypothalamus and in your fat cells is to become insulin resistant meaning to not grow when you eat saturated fats”

“so we want to have lots of saturated fat in our diet stearic acid and palmitic acid to make your fat cells not grow and you will remain insulin sensitive”

“the way to undo that in my opinion is to eat much higher amounts of suet and saturated fat you must replace the linoleic acid in your fat cells with saturated fat so they can become insulin resistant so they don't grow when they see insulin”

“how do you fix it you eat lots of saturated fatty acids specifically long-chain saturated fatty acids stearic acid and palmitic acid from grass-fed grass-finished meat in your diet you get all of those linoleic acid containing foods out”

“how do you get an insulin resistant adipocyte you don't feed your body linoleic acid you eat saturated fatty acids which are the fatty acids that have been vilified for the last 70 years thank you ansel keys wrongly as i will talk about in the podcast with me and ty colts and as the journal of the american cardiology association is saying but they're not connecting all these mechanisms you want your fat cells insulin resistant so that the rest of your body can be insulin sensitive get it”

“if you are eating saturated fat like stearic acid and palmitic acid your fat cells become insulin resistant and they don't grow and this is where things get a little complicated as your fat cells grow there is another enzyme in the fat cell called atgl and atgl works in concert with something called perilipin a to release free fatty acids into your blood and the free fatty acids into your blood are what signal to the rest of the body whether your body should be insulin resistant or insulin sensitive right so we have insulin resistance at the fat cell which is going to signal to the rest of the body”

“the way you get fat cells that are insulin resistant is by eating saturated fat and this has been shown time and time again that if you increase the amount of palmitic acid and stearic acid in the diet your fat cells become insulin resistant which means that when insulin spikes with a meal and insulin signals to those adipocytes to grow they won't respond those adipocytes won't take up glucose and they won't take up lipids and become bigger fat cells”

“if you increase the amount of palmitic acid and stearic acid in the diet your fat cells become insulin resistant”

“how do you make your visceral adipose tissue insulin resistant you eat stearic acid”

“saturated fat equals more reactive oxygen species especially at the level of the adipocyte which makes the adipocyte insulin resistant because that superoxide becomes hydrogen peroxide turns off the insulin receptor on the surface of the adipocyte the adipocyte doesn't grow the hepatite doesn't grow and in fact it shrinks because it's feeding fat to the rest of the body”

“stearic acid appears to make our fat cells insulin resistant which makes them not grow”

“if you want to be insulin sensitive which if you want to be metabolically healthy you want your adipocytes small how do you get small adipocytes you tell those adipocytes to shut off to stop growing by giving them saturated fat which is the signal to stop growing”

“it is true that level with that cell the the saturated fat does appear to cause insulin resistance but that's probably a good thing because it doesn't grow right it doesn't it doesn't grow it shrinks”