The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
saturated fat does not cause the same type of insulin physiology that you guys are claiming fat and low carbohydrate diets can cause glucose sparing in the muscle and we can talk about why but they are not causing physiologic insulin resistance or pathologic insulin resistance in the same way
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
but in type-2 diabetes it's a very different situation and as you and I have talked about insulin resistance systemic pathologic insulin resistance we wanted I want to talk about what you think causes that but I think one of the main things that causes it is mixed carbohydrate and fat overfeeding so we get lots of calories the adipocytes are stuffed full of lipids and the adipocytes are saying whoa I am full to my brim and the adipocytes become insulin-resistant they refuse the actions of insulin and the adipocytes are initiating this cascade and they're doing the same thing which is why it looks confusing they're they're shifting to palmitate they're telling the muscles to stop refusing glucose and the signals of insulin but it's coming from the adipocytes because in many situations they are over full of calories in the form of fatty acids and in that situation insulin is high yeah and glucose is high right
in type 2 diabetes it's a very different situation and as you and i have talked about insulin resistance systemic pathologic insulin resistance we want to i want to talk about what you think causes that but i think one of the main things that causes it is mixed carbohydrate and fat over feeding so we get lots of calories the adipocytes are stuffed full of lipids and the adipocytes are saying whoa i am full to my brim and the adipocytes become insulin resistant they refuse the actions of insulin and the adipocytes are initiating this cascade and they're doing the same thing which is why it looks confusing they're they're shifting to palmitate they're telling the muscles to stop refusing uh glucose and the signals of insulin but it's coming from the adipocytes because in many situations they are over full of calories in the form of fatty acids and in that situation insulin is high yeah and glucose is high right