The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
What we know is that there are very high rates of insulin resistance in East and Southeast Asians and um in those of African descent. And so in those populations as well, you might look skinny and have a lot of visceral atapost tissue and be very insulin resistant.
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we know that a people of different ethnicities can get a certain amount of fat before they become instant resistant Caucasians were amazing like we can we can stuff a whole boatload of fat into our bodies before we get types you may make to store the fat we can store you can expand exactly and we can get dietary fat per se no we're talking about how expand yes so Caucasians generally can get the fattest again on average before they become insulin resistant whereas people of different say South Asian Asian populations they can get less fats before they become insulin resistant
in Asian populations that threshold at which the dipper site tops out is much lower
there is at some level uh a genetic effect or an ethnic effect because we know that people of different ethnicities can get a certain amount of fat um before they become insulin resistant caucasians were amazing like we can we can stuff a whole boatload of fat into our bodies before we get types you mean we can store the fat we can store you can expand yeah exactly and we can get not dietary fat per se no not dietary yeah we're talking about how much can expand yeah so so caucasians generally can get the fattest again on average before they become insulin resistant whereas people of of different um say south asian asian populations um they can get less fat before they become insulin resistant
so South Asians and East Asians develop such acute inflammation insulin resistance of low body weights because the proportion of that visceral fat is significantly higher
Earlier I'd mentioned and it's a perfect opportunity to bring in different ethnicities because different ethnicities will store fat differently. And this all is underlying the earlier conversation of the slow insulin resistance where I said it starts in the fat cell and I very much advocate that view.