Trans fats are harmful for the endothelium and contribute to insulin resistance, whereas polyunsaturated fats do not have the same negative impact when replacing saturated fats containing trans fats.

“saturated fat all saturated fats are not created equally we know that trans fats are harmful for the endothelium harmful in terms of insulin resistance versus insulin sensitivity replacing saturated fat that contains significant amounts of trans fats with polyunsaturated fat tells us nothing about replacing animal fats hallow butter or ghee with polyunsaturated seed oils in terms of insulin resistance”