Paul Saladino· MD
first thing that happens I think in most people you can probably become insulin-resistant in your muscle tissue first if you just like sit all day and do not move that muscle at all
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
first thing that happens I think in most people you can probably become insulin-resistant in your muscle tissue first if you just like sit all day and do not move that muscle at all
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you know, one of my good friends here, Dr. Gabrielle Lyon, that I always talk about insulin resistance, you know, generally starts in your skeletal muscle. You know, 80% of your glucose is getting disposed of in your skeletal muscle.
insulin resistance you know generally starts in your skeletal muscle you know 80 of your glucose is getting disposed of your skeletal muscle
So when you do exercise, as you say, first your insulin sensitivity increases. So you don't need so much insulin. And as I said earlier, the first tissue that develops type 2 diabetes or insulin resistance is the skeletal muscle.
But, you know, generally exercise increases insulin sensitivity.