Clinically identifying individuals in the early stages of insulin resistance is crucial for counseling and avoiding downstream consequences.

“But in its earliest stages the glucose is still normal but there's this cold war happening in the body where the insulin levels are still two or three or four times higher than they used to be.”

“People much of modern clinical care has what I call a glucosecentric paradigm when it comes to monitoring metabolic health or even cardioabolic health given how relevant diabetes and metabolic problems are to cardiovascular disease. But the the consequence of the glucosecentric paradigm and there's reasons for it. So I don't mean to s to state this in any kind of incriminating way. They they have their own justification for the glucosecentric paradigm, but it's increasingly harder to overlook because of what we know with regards to insulin.”

“So insulin resistance in its earliest stages is high insulin but normal glucose.”