Paul Saladino· MD
how can anyone be so myopically focused on ldl in uh in absence or in exclusion of the context of oxidized ldl lp little a which are much better predictors of cardiovascular risk than ldl itself
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
how can anyone be so myopically focused on ldl in uh in absence or in exclusion of the context of oxidized ldl lp little a which are much better predictors of cardiovascular risk than ldl itself
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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ldlsc was associated with incident cardiovascular disease only when LP little a cholesterol content was included in the measurement so they're saying that if you correct LDL for LP little a it's not even a risk factor for cardiovascular disease anymore