The notion that LDL cholesterol alone is sufficient to initiate atherosclerotic plaque and is the main driver of atherosclerosis is likely to be disproven.

“but this idea that I think I just I love this concept that LD there's so much evidence that LDL is not what is driving atherosclerosis or Mason whether it's the pathological inconsistencies whether it's the timeline whether it's all of the stuff that I've talked about previously and I talked about much more in the book about inconsistencies in labels of LDL and risk of coronary artery disease other things that are much bigger risks the statin should have fun stuff like drugs that lower LD vent coronary events drugs that lower LDL and don't prevent coronary events right exactly so yeah it's just yeah there's so many things that argue against the notion that LDL alone is number one enough to initiate an athletic plaque and number two really the main driver of atherosclerosis moving forward”

“this is why the ldl thing is like the major uh crutch or the major i think stumbling around for people because they're going to say no anything that lowers equal b must be good for humans and when you release when you release the demons when you exercise the [ __ ] demons of ldl and you realize oh holy [ __ ] maybe ldl isn't the end all be all maybe rising ldl if such a fact isn't the end of the world then you start to it all starts to make sense”

“it doesn't make any sense to just go really hard on this especially because we're seeing people where LDL is super high and they're not having the they're not having high plaque burdens they're not seeing increased risk of cardiovascular disease”