While the correlation between elevated LDL and improved outcomes in infection is not causal, LDL is beneficial to the immune system.

“the mice that had higher levels of LDL seemed to have much better survival much much much five versus a hundred five percent died versus one hundred percent died in the group with a regular or low LDL right”

“but actually if an LDL helps to the immune system to bind to to bacteria to isolate them in air Ireland to be absorbed by white cells so they have quite strong function to play an amine in in the immune system and if you look at people with higher LDL levels are less likely to die of sepsis etc etc they have that's that's not the primary role but it obviously developed and and that's become part of a thing that they do because the body's decided it boats around in the body we're better get it to do more than one thing we're good to do a few things and this is one of the things that it does and of course ourselves absolutely require cholesterol they need it otherwise you would never think of an LDL receptor”

“not LDL has been shown to quench these endotoxins right so this is I want to just reiterate this for all the listeners that in settings of sepsis and this is what we talked about higher l do is probably protective because all of these exotoxins and or more specifically endotoxin live a polysaccharide LDL can manage those and prevent toxicity around those”

“ldl has critical immune functions in the human body which i'll show you guys a little later it interrupts quorum sensing which is the communication between bacteria and we know in both animal and human experiments that if you decrease the ldl animals get more sick and in humans who have lower levels of ldl they have increased rates of communicable infectious disease so ldl is an immune particle”