David Sinclair· PhD
Lifespan extension by BHB was reported in worms a decade ago, dependent on the NAD-dependent sirtuin, Sir-2.1
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
Lifespan extension by BHB was reported in worms a decade ago, dependent on the NAD-dependent sirtuin, Sir-2.1
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showed that you could also over express the worm version of sir to an extended lifespan and C elegans