Andrew Huberman· PhD
Well, the bitter receptors create a what we call labeled line, a unique trajectory to the neurons of the brainstem that control the [gags], the gag reflex.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
Well, the bitter receptors create a what we call labeled line, a unique trajectory to the neurons of the brainstem that control the [gags], the gag reflex.
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Bitter receptors are there to make sure we don't ingest things that are poisonous. How do I know this? How can I say that? Even though I was definitely not consulted at the design phase, how can I say that? Well, the bitter receptors create a what we call labeled line, a unique trajectory to the neurons of the brainstem that control the [gags], the gag reflex. If we taste something very bitter it automatically triggers the gag reflex.
bitter is particularly enriched at the very back of your tongue and there is a teological basis for that actually a biological basis for that. That's the last line of defense before you swallow something bad. And so let's make sure that the very back of your tongue has plenty of these bad news receptors so that if they get activated you can trigger a gagging reflex and get rid of this that otherwise may kill you.