The spectrum of physical dependence symptoms associated with kratom use varies by product type and is not well understood.

“So there there's not only is there a spectrum of of physical dependence symptoms um you know you you have this spectrum of products and which ones are causing which we don't we don't have a handle on yet.”

“It does. It absolutely causes a physical dependence. You said it absolutely causes a physical dependence. Do you mean it absolutely causes a physical dependence at every dose and every desired effect? >> I would I would say not. So if you take it one time, you're not going to be physically dependent on it. But if you're utilizing it over a course of time, and I can't tell you what that time frame is because we don't have any chronic studies in humans.”